Susan Calman was born on 6 November 1974 in Glasgow, Scotland. Her father, Kenneth Calman, is a prominent medical professional.

She studied law at the University of Glasgow and initially trained as a corporate lawyer before leaving the profession to pursue a career in comedy.

Calman rose to prominence through stand-up and BBC Radio 4, writing and starring in shows such as Sisters and Keep Calman Carry On. Her distinctive humour and storytelling led to wider television opportunities.

In 2019, she was announced as presenter of Great British Menu (BBC Two), hosting the 2020 series and guiding viewers through the competition.

She continues to work in television, radio, and writing, living in Scotland with her wife while maintaining a high-profile career in UK entertainment.